Permethrin 5% Cream is a topical antiparasitic medication used for the treatment of scabies infestations caused by Sarcoptes scabiei mites. It belongs to the synthetic pyrethroid class and works by disrupting the sodium channel currents in the nerve cell membranes of parasites, leading to paralysis and death of mites and their eggs. Permethrin 5% is considered the first-line treatment for scabies due to its high efficacy, safety profile, and minimal systemic absorption when applied topically. It provides rapid relief from itching, redness, and skin irritation associated with mite infestation. The cream is suitable for adults and children above 2 months of age when used under medical supervision. The formulation ensures deep skin penetration to eradicate mites in burrows while being gentle on the skin.
