This advanced triple-combination topical formulation contains Hydroquinone 4% w/w, Tretinoin 0.05% w/w, and Fluocinolone Acetonide 0.01% w/w. It is commonly prescribed for the short-term treatment of moderate to severe melasma and hyperpigmentation disorders. Hydroquinone 4% – A potent skin-lightening agent that reduces melanin production by inhibiting tyrosinase enzyme activity. It helps fade dark patches, melasma, freckles, and post-inflammatory hyperpigmentation. Tretinoin 0.05% – A vitamin A derivative that accelerates skin cell turnover, enhances penetration of hydroquinone, and improves overall skin texture. Fluocinolone acetonide 0.01% – A mild corticosteroid that reduces inflammation, redness, irritation, and itching associated with retinoid therapy. This synergistic combination helps lighten stubborn pigmentation while minimizing irritation and inflammation, making it effective for melasma, sun-induced pigmentation, and dark spots.
